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Drug Name | NTX-1088 |
Trade Name | |
Synonyms | NTX 1088|NTX1088 |
Drug Descriptions |
NTX-1088 is a monoclonal antibody that targets the poliovirus receptor (PVR, CD155), thereby preventing its interaction with CD96 and TIGIT as well as DNAM1 (CD226), potentially leading to enhanced antitumor immune response and inhibition of tumor growth (Cancer Immunol Res 2022;10(1 Suppl):Abstract nr P075). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C188066 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
NTX-1088 | NTX-1088 | 0 | 1 |
NTX-1088 + Pembrolizumab | NTX-1088 Pembrolizumab | 0 | 1 |