TAK-280
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| Drug Name | TAK-280 |
| Trade Name | |
| Synonyms | TAK 280|TAK280|MVC280|MVC-280|MVC 280 |
| Drug Descriptions |
TAK-280 is a conditional bispecific redirected activation T-cell engager targeting CD276 (B7-H3) and CD3, which is activated in the tumor microenvironment and redirects cytotoxic T-lymphocytes towards tumor cells expressing CD276 (B7-H3), potentially resulting in increased tumor cell killing (J Clin Oncol 2025 43: 16_suppl, TPS2684, NCI Drug Dictionary). |
| DrugClasses | CD276 Antibody 21 CD3 Antibody 119 |
| CAS Registry Number | NA |
| NCIT ID | C200591 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| TAK-280 | TAK-280 | 0 | 1 |
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