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Drug Name | RYZ101 |
Trade Name | |
Synonyms | RYZ-101|RYZ 101|225Ac-DOTATATE RYZ101 |
Drug Descriptions |
RYZ101 is a radioconjugate comprising a somatostatin analog linked to Actinium-225, which delivers radiation to tumor cells expressing SSTRs with a high affinity for SSTR2, potentially inhibiting tumor growth (PMID: 37616528). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C189915 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Atezolizumab + Carboplatin + Etoposide + RYZ101 | Atezolizumab Carboplatin Etoposide RYZ101 | 0 | 1 |
Carboplatin + Etoposide + RYZ101 | Carboplatin Etoposide RYZ101 | 0 | 0 |
Pembrolizumab + RYZ101 | Pembrolizumab RYZ101 | 0 | 1 |
RYZ101 | RYZ101 | 0 | 3 |