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| Drug Name | XMT-2056 |
| Trade Name | |
| Synonyms | XMT2056|XMT 2056 |
| Drug Descriptions |
XMT-2056 is an antibody-drug conjugate (ADC) comprising an ERBB2 (HER2)-targeting antibody conjugated to a STING agonist, which potentially induces an anti-tumor immune response and inhibits tumor growth (Cancer Res 2022;82(12_Suppl):Abstract nr 3503). |
| DrugClasses | HER2 (ERBB2) Antibody 79 HER2 (ERBB2) Antibody-Drug Conjugate 35 STING1 Agonist 21 |
| CAS Registry Number | NA |
| NCIT ID | C190297 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Pertuzumab + XMT-2056 | Pertuzumab XMT-2056 | 0 | 0 |
| Trastuzumab + XMT-2056 | Trastuzumab XMT-2056 | 0 | 0 |
| Trastuzumab deruxtecan + XMT-2056 | Trastuzumab deruxtecan XMT-2056 | 0 | 0 |
| unspecified PD-1 antibody + XMT-2056 | XMT-2056 unspecified PD-1 antibody | 0 | 0 |
| XMT-2056 | XMT-2056 | 0 | 1 |