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Drug Detail
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| Drug Name | RLY-5836 |
| Trade Name | |
| Synonyms | RLY 5836|RLY5836 |
| Drug Descriptions |
RLY-5836 is a mutant-selective PIK3CA inhibitor, which potentially induces apoptosis and inhibits growth of tumor cells expressing mutant PIK3CA (Cancer Res (2024) 84 (9_Supplement): PO3-20-04, NCI Drug Dictionary). |
| DrugClasses | PIK3CA inhibitor 26 |
| CAS Registry Number | NA |
| NCIT ID | C199577 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Abemaciclib + Fulvestrant + RLY-5836 | Abemaciclib Fulvestrant RLY-5836 | 0 | 1 |
| Fulvestrant + Palbociclib + RLY-5836 | Fulvestrant Palbociclib RLY-5836 | 0 | 1 |
| Fulvestrant + Ribociclib + RLY-5836 | Fulvestrant RLY-5836 Ribociclib | 0 | 1 |
| Fulvestrant + RLY-5836 | Fulvestrant RLY-5836 | 0 | 1 |
| RLY-5836 | RLY-5836 | 0 | 1 |
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