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Drug Name | RLY-5836 |
Trade Name | |
Synonyms | RLY 5836|RLY5836 |
Drug Descriptions |
RLY-5836 is a mutant-selective PIK3CA inhibitor, which potentially induces apoptosis and inhibits growth of tumor cells expressing mutant PIK3CA (Cancer Res (2024) 84 (9_Supplement): PO3-20-04, NCI Drug Dictionary). |
DrugClasses | PIK3CA inhibitor 25 |
CAS Registry Number | NA |
NCIT ID | C199577 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Abemaciclib + Fulvestrant + RLY-5836 | Abemaciclib Fulvestrant RLY-5836 | 0 | 1 |
Fulvestrant + Palbociclib + RLY-5836 | Fulvestrant Palbociclib RLY-5836 | 0 | 1 |
Fulvestrant + Ribociclib + RLY-5836 | Fulvestrant RLY-5836 Ribociclib | 0 | 1 |
Fulvestrant + RLY-5836 | Fulvestrant RLY-5836 | 0 | 1 |
RLY-5836 | RLY-5836 | 0 | 1 |