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Drug Name | Ribociclib |
Trade Name | Kisqali |
Synonyms | LEE011|LEE-011|LEE 011 |
Drug Descriptions |
Kisqali (ribociclib) is a dual CDK4/6 inhibitor, which may induce cell cycle arrest and reduce proliferation in cancer cells (PMID: 24045179). Kisqali (ribociclib) is FDA-approved in combination with an aromatase inhibitor in women with hormone receptor-positive, ERBB2 (HER2)-negative breast cancer, and in combination with Faslodex (fulvestrant) in postmenopausal women with hormone receptor-positive, ERBB2 (HER2)-negative breast cancer (FDA.gov). |
DrugClasses | CDK4/6 Inhibitor 14 |
CAS Registry Number | 1211441-98-3 |
NCIT ID | C95701 |