DB-1311
Drug Detail
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| Drug Name | DB-1311 |
| Trade Name | |
| Synonyms | DB 1311|DB1311|BNT324|BNT-324|BNT 324 |
| Drug Descriptions |
DB-1311 is an antibody-drug conjugate (ADC) comprising a B7-H3 (CD276) antibody conjugated to the topoisomerase inhibitor P1021, which potentially decreases growth of B7-H3 (CD276)-expressing tumors (Cancer Res (2023) 83 (7_Supplement): 2967). |
| DrugClasses | CD276 Antibody 21 |
| CAS Registry Number | NA |
| NCIT ID | C208267 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Abiraterone + DB-1311 | Abiraterone DB-1311 | 0 | 1 |
| BNT327 + DB-1311 | BNT327 DB-1311 | 0 | 2 |
| DB-1305 + DB-1311 | DB-1305 DB-1311 | 0 | 1 |
| DB-1311 | DB-1311 | 0 | 1 |
| DB-1311 + Enzalutamide | DB-1311 Enzalutamide | 0 | 1 |
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