Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | CARv3-TEAM-E T-cells |
Trade Name | |
Synonyms | |
Drug Descriptions |
CARv3-TEAM-E T-cells are autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting EGFRvIII and a T-cell engaging antibody molecule (TEAM) comprising a bispecific T-cell engager (BiTE) targeting wild-type EGFR, which potentially induce killing of tumor cells expressing EGFRvIII and wild-type EGFR (PMID: 38477966). |
DrugClasses | CD3 Antibody 99 EGFR Antibody 60 |
CAS Registry Number | NA |
NCIT ID | C198499 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CARv3-TEAM-E T-cells | CARv3-TEAM-E T-cells | 0 | 1 |