CARv3-TEAM-E T-cells
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| Drug Name | CARv3-TEAM-E T-cells |
| Trade Name | |
| Synonyms | |
| Drug Descriptions |
CARv3-TEAM-E T-cells are autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting EGFRvIII and a T-cell engaging antibody molecule (TEAM) comprising a bispecific T-cell engager (BiTE) targeting wild-type EGFR, which potentially induce killing of tumor cells expressing EGFRvIII and wild-type EGFR (PMID: 38477966). |
| DrugClasses | CD3 Antibody 119 EGFR Antibody 73 |
| CAS Registry Number | NA |
| NCIT ID | C198499 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| CARv3-TEAM-E T-cells | CARv3-TEAM-E T-cells | 0 | 1 |
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