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Drug Name | DK210 |
Trade Name | |
Synonyms | DK-210|DK 210 |
Drug Descriptions |
DK210 is a dual cytokine fusion protein comprising high-affinity IL-10 linked to IL-2 by an anti-EGFR single chain variable fragment, which binds to EGFR and potentially induces a cytotoxic T-lymphocyte (CTL) response against tumor cells (J Clin Oncol 42, 2024 (suppl 16; abstr 2584), NCI Drug Dictionary). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C201499 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
DK210 | DK210 | 0 | 1 |
DK210 + Nivolumab | DK210 Nivolumab | 0 | 1 |
DK210 + Pembrolizumab | DK210 Pembrolizumab | 0 | 1 |