Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name JZP898
Trade Name
Synonyms JZP-898|JZP 898|WTX-613|WTX613
Drug Descriptions

JZP898 comprises IFNalpha2b linked to half-life extension domains by protease-sensitive linkers that are cleaved to in the presence of proteases in the tumor microenvironment to release IFNalpha2b, potentially inducing IFNalpha signaling and increased anti-tumor immune response (Cancer Res (2023) 83 (7_Supplement):1817).

DrugClasses
CAS Registry Number NA
NCIT ID NA

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
JZP898 JZP898 0 1
JZP898 + Pembrolizumab JZP898 Pembrolizumab 0 1


Additional content available in CKB BOOST