HRO761
Drug Detail
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| Drug Name | HRO761 |
| Trade Name | |
| Synonyms | HRO-761|HRO 761 |
| Drug Descriptions |
HRO761 inhibits WRN, locking it in an inactive conformation, which leads to activation of the DNA damage response and potentially inhibiting tumor growth (PMID: 38658754). |
| DrugClasses | WRN Inhibitor 5 |
| CAS Registry Number | 2869954-34-5 |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| HRO761 | HRO761 | 0 | 1 |
| HRO761 + Irinotecan | HRO761 Irinotecan | 0 | 1 |
| HRO761 + Pembrolizumab | HRO761 Pembrolizumab | 0 | 1 |
| HRO761 + Tislelizumab | HRO761 Tislelizumab | 0 | 0 |
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