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Drug Detail
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| Drug Name | Tislelizumab |
| Trade Name | Tevimbra |
| Synonyms | BGB-A317|tislelizumab-jsgr |
| Drug Descriptions |
Tevimbra (tislelizumab) is a human monoclonal antibody that targets PD-1 (PDCD1), thereby blocking the binding of PD-L1 (CD274) and potentially resulting in activation of a T-cell immune response against tumor cells (PMID: 32769013, PMID: 32561638, PMID: 32540858). Tevimbra (tislelizumab) is FDA-approved for use in patients with unresectable or metastatic esophageal squamous cell carcinoma (FDA.gov). |
| DrugClasses | Immune Checkpoint Inhibitor 149 PD-L1/PD-1 antibody 124 |
| CAS Registry Number | 1858168-59-8 |
| NCIT ID | C121775 |
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