BTX-6654
Drug Detail
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| Drug Name | BTX-6654 |
| Trade Name | |
| Synonyms | BTX6654|BTX 6654 |
| Drug Descriptions |
BTX-6654 is a bifunctional SOS1 degrader that potentially decreases downstream KRAS signaling and inhibits tumor growth (PMID: 38224565). |
| DrugClasses | SOS1 Inhibitor 17 |
| CAS Registry Number | NA |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Afatinib + BTX-6654 | Afatinib BTX-6654 | 0 | 0 |
| BTX-6654 | BTX-6654 | 1 | 0 |
| BTX-6654 + MRTX-1133 | BTX-6654 MRTX-1133 | 0 | 0 |
| BTX-6654 + Sotorasib | BTX-6654 Sotorasib | 0 | 0 |
| BTX-6654 + Trametinib | BTX-6654 Trametinib | 0 | 0 |
CKB BOOST