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Drug Name | BTX-6654 |
Trade Name | |
Synonyms | BTX6654|BTX 6654 |
Drug Descriptions |
BTX-6654 is a bifunctional SOS1 degrader that potentially decreases downstream KRAS signaling and inhibits tumor growth (PMID: 38224565). |
DrugClasses | SOS1 Inhibitor 16 |
CAS Registry Number | NA |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Afatinib + BTX-6654 | Afatinib BTX-6654 | 0 | 0 |
BTX-6654 | BTX-6654 | 1 | 0 |
BTX-6654 + MRTX-1133 | BTX-6654 MRTX-1133 | 0 | 0 |
BTX-6654 + Sotorasib | BTX-6654 Sotorasib | 0 | 0 |
BTX-6654 + Trametinib | BTX-6654 Trametinib | 0 | 0 |