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Drug Name BTX-6654
Trade Name
Synonyms BTX6654|BTX 6654
Drug Descriptions

BTX-6654 is a bifunctional SOS1 degrader that potentially decreases downstream KRAS signaling and inhibits tumor growth (PMID: 38224565).

DrugClasses SOS1 Inhibitor 16
CAS Registry Number NA
NCIT ID NA

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Afatinib + BTX-6654 Afatinib BTX-6654 0 0
BTX-6654 BTX-6654 1 0
BTX-6654 + MRTX-1133 BTX-6654 MRTX-1133 0 0
BTX-6654 + Sotorasib BTX-6654 Sotorasib 0 0
BTX-6654 + Trametinib BTX-6654 Trametinib 0 0


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