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Drug Name | MRTX-1133 |
Trade Name | |
Synonyms | MRTX1133|MRTX 1133 |
Drug Descriptions |
MRTX-1133 selectively inhibits KRAS G12D, which results in decreased downstream signaling and potentially leads to reduced tumor growth (PMID: 34889605). |
DrugClasses | KRAS G12D Inhibitor 16 |
CAS Registry Number | NA |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Afatinib + MRTX-1133 | Afatinib MRTX-1133 | 0 | 0 |
Alpelisib + MRTX-1133 | Alpelisib MRTX-1133 | 0 | 0 |
BTX-6654 + MRTX-1133 | BTX-6654 MRTX-1133 | 0 | 0 |
BTX-7312 + MRTX-1133 | BTX-7312 MRTX-1133 | 0 | 0 |
Canertinib + MRTX-1133 | Canertinib MRTX-1133 | 0 | 0 |
Cetuximab + MRTX-1133 | Cetuximab MRTX-1133 | 0 | 0 |
Erlotinib + MRTX-1133 | Erlotinib MRTX-1133 | 0 | 0 |
Gemcitabine + MRTX-1133 + Nab-paclitaxel | Gemcitabine MRTX-1133 Nab-paclitaxel | 0 | 0 |
IAG933 + MRTX-1133 | IAG933 MRTX-1133 | 0 | 0 |
KO-2806 + MRTX-1133 | KO-2806 MRTX-1133 | 0 | 0 |
Lapatinib + MRTX-1133 | Lapatinib MRTX-1133 | 0 | 0 |
MRTX-1133 | MRTX-1133 | 5 | 1 |
MRTX-1133 + MRTX1719 | MRTX-1133 MRTX1719 | 0 | 0 |
MRTX-1133 + Neratinib | MRTX-1133 Neratinib | 0 | 0 |
MRTX-1133 + RGT-018 | MRTX-1133 RGT-018 | 0 | 0 |
MRTX-1133 + TNO155 | MRTX-1133 TNO155 | 0 | 0 |
MRTX-1133 + Trametinib | MRTX-1133 Trametinib | 0 | 0 |
MRTX-1133 + Ulixertinib | MRTX-1133 Ulixertinib | 0 | 0 |