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Drug Name | IBI354 |
Trade Name | |
Synonyms | IBI-354|IBI 354 |
Drug Descriptions |
IBI354 is an antibody-drug conjugate (ADC) comprising the ERBB2 (HER2) antibody trastuzumab linked to a toposiomerase I inhibitor, which potentially induces cell cycle arrest and apoptosis in Erbb2 (Her2)-expressing tumor cells and results in antitumor activity (NCI Drug Dictionary, Ann Oncol (2024) 35 (suppl_2): S467-468). |
DrugClasses | HER2 (ERBB2) Antibody-Drug Conjugate 31 |
CAS Registry Number | NA |
NCIT ID | C198994 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
IBI354 | IBI354 | 0 | 1 |