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Therapy Name | IBI354 |
Synonyms | |
Therapy Description |
IBI354 is an antibody-drug conjugate (ADC) comprising the ERBB2 (HER2) antibody trastuzumab linked to a toposiomerase I inhibitor, which potentially induces cell cycle arrest and apoptosis in Erbb2 (Her2)-expressing tumor cells and results in antitumor activity (NCI Drug Dictionary, Ann Oncol (2024) 35 (suppl_2): S467-468). |