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| Drug Name | LV20.19 CAR-T cells |
| Trade Name | |
| Synonyms | Autologous CAR-20/19-T cells|4-1BB-CD3zeta LV20.19 CAR T cells |
| Drug Descriptions |
LV20.19 CAR-T cells are autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) comprising single chain variable fragments targeting CD19 and CD20 coupled to CD3zeta and TNFRSF9 (CD137; 4-1BB) signaling domains, which potentially induce antitumor activity (PMID: 33020647, NCI Drug Dictionary). |
| DrugClasses | CD19 Immune Cell Therapy 65 CD20 Immune Cell Therapy 13 |
| CAS Registry Number | NA |
| NCIT ID | C143156 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| LV20.19 CAR-T cells | LV20.19 CAR-T cells | 0 | 0 |
| LV20.19 CAR-T cells + Pirtobrutinib | LV20.19 CAR-T cells Pirtobrutinib | 0 | 1 |
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