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Drug Name | Aflibercept |
Trade Name | Zaltrap |
Synonyms | AVE 0005|Eylea|Ziv-Aflibercept |
Drug Descriptions |
Zaltrap (aflibercept) is comprised of human IgG fused to the extracellular domains of VEGFR1 and VEGFR2, which binds VEGF to inhibit tumor angiogenesis and metastasis. Zaltrap (aflibercept) is FDA approved in patients with metastatic colorectal cancer (FDA.gov). |
DrugClasses | VEGF Antibody 12 VEGFR Inhibitor (Pan) 36 |
CAS Registry Number | 862111-32-8 |
NCIT ID | C2682 |