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Drug Detail

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Drug Name Luminespib
Trade Name
Synonyms AUY922|NVP-AUY922
Drug Descriptions

Luminespib (AUY922) inhibits HSP90, resulting in increased tumor cell apoptosis and decreased tumor cell angiogenesis and proliferation (PMID: 25955495, PMID: 18413753, PMID: 32592377).

DrugClasses HSP90 Inhibitor 35
CAS Registry Number 747412-64-2
NCIT ID C71467

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cetuximab + Luminespib Cetuximab Luminespib 0 1
Erlotinib + Luminespib Erlotinib Luminespib 0 0
Luminespib Luminespib 2 4
Luminespib + Pemetrexed Disodium Luminespib Pemetrexed Disodium 0 1
Luminespib + Sirolimus Luminespib Sirolimus 0 0
Luminespib + Torin 1 Luminespib Torin 1 0 0


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