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Drug Name | Luminespib |
Trade Name | |
Synonyms | AUY922|NVP-AUY922 |
Drug Descriptions |
Luminespib (AUY922) inhibits HSP90, resulting in increased tumor cell apoptosis and decreased tumor cell angiogenesis and proliferation (PMID: 25955495, PMID: 18413753, PMID: 32592377). |
DrugClasses | HSP90 Inhibitor 35 |
CAS Registry Number | 747412-64-2 |
NCIT ID | C71467 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cetuximab + Luminespib | Cetuximab Luminespib | 0 | 1 |
Erlotinib + Luminespib | Erlotinib Luminespib | 0 | 0 |
Luminespib | Luminespib | 2 | 4 |
Luminespib + Pemetrexed Disodium | Luminespib Pemetrexed Disodium | 0 | 1 |
Luminespib + Sirolimus | Luminespib Sirolimus | 1 | 0 |
Luminespib + Torin 1 | Luminespib Torin 1 | 1 | 0 |