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Drug Name | Perifosine |
Trade Name | |
Synonyms | KRX-0401|NSC-639966 |
Drug Descriptions |
Perifosine (KRX-0401) is a synthetic alkylphospholipid that inhibits AKT resulting in apoptotic induction and antitumor activity (PMID: 16418332, PMID: 28864978, PMID: 31325145). |
DrugClasses | Akt Inhibitor (Pan) 21 |
CAS Registry Number | 157716-52-4 |
NCIT ID | C1727 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
ABT-737 + Perifosine | ABT-737 Perifosine | 0 | 0 |
Cisplatin + Perifosine | Cisplatin Perifosine | 0 | 0 |
Gefitinib + Perifosine | Gefitinib Perifosine | 0 | 0 |
Lapatinib + Perifosine | Lapatinib Perifosine | 0 | 0 |
Perifosine | Perifosine | 3 | 1 |
Perifosine + Temsirolimus | Perifosine Temsirolimus | 0 | 1 |