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| Drug Name | Gefitinib |
| Trade Name | Iressa |
| Synonyms | ZD1839 |
| Drug Descriptions |
Iressa (gefitinib) is a first-generation EGFR inhibitor that binds EGFR and inhibits downstream signaling, potentially resulting in decreased growth of tumors with EGFR activation (PMID: 26980062, PMID: 25302162, PMID: 15284455). Iressa (gefitinib) is FDA approved for use in patients with non-small cell lung cancer harboring an EGFR exon 19 deletion or EGFR L858R (FDA.gov). |
| DrugClasses | EGFR Inhibitor (Pan) 62 EGFR Inhibitor 1st gen 3 |
| CAS Registry Number | 184475-35-2 |
| NCIT ID | C1855 |
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