Perifosine
Drug Detail
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| Drug Name | Perifosine |
| Trade Name | |
| Synonyms | KRX-0401|NSC-639966 |
| Drug Descriptions |
Perifosine (KRX-0401) is a synthetic alkylphospholipid that inhibits AKT resulting in apoptotic induction and antitumor activity (PMID: 16418332, PMID: 28864978, PMID: 31325145). |
| DrugClasses | Akt Inhibitor (Pan) 22 |
| CAS Registry Number | 157716-52-4 |
| NCIT ID | C1727 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| ABT-737 + Perifosine | ABT-737 Perifosine | 0 | 0 |
| Cisplatin + Perifosine | Cisplatin Perifosine | 0 | 0 |
| Gefitinib + Perifosine | Gefitinib Perifosine | 0 | 0 |
| Lapatinib + Perifosine | Lapatinib Perifosine | 0 | 0 |
| Perifosine | Perifosine | 3 | 1 |
| Perifosine + Temsirolimus | Perifosine Temsirolimus | 0 | 1 |
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