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Drug Name | PF-04217903 |
Trade Name | |
Synonyms | PF04217903 |
Drug Descriptions |
PF-04217903 binds to MET and inhibits its activation, resulting in decreased activation of downstream signaling, and potentially resulting in decreased tumor cell growth and migration and increased tumor cell death (PMID: 28599617). |
DrugClasses | MET Inhibitor 59 |
CAS Registry Number | 956905-27-4 |
NCIT ID | C78483 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CGM097 + Dabrafenib + Navitoclax + PF-04217903 | CGM097 Dabrafenib Navitoclax PF-04217903 | 1 | 0 |
PF-04217903 | PF-04217903 | 0 | 0 |
PF-04217903 + PF-04880594 | PF-04217903 PF-04880594 | 0 | 0 |