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Drug Name | Sapitinib |
Trade Name | |
Synonyms | AZD8931|AZD-8931 |
Drug Descriptions |
Sapitinib (AZD-8931) binds to and inhibits the ERBB family members EGFR, ERBB2 (HER2), and ERBB3, which may lead to decreased tumor cell proliferation and increased apoptosis (PMID: 20145185, PMID: 31765988). |
DrugClasses | EGFR Inhibitor (Pan) 62 HER2 Inhibitor 42 HER3 Inhibitor 1 |
CAS Registry Number | 848942-61-0 |
NCIT ID | C77887 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Atezolizumab + Sapitinib | Atezolizumab Sapitinib | 0 | 0 |
Capecitabine + Oxaliplatin + Sapitinib | Capecitabine Oxaliplatin Sapitinib | 0 | 0 |
Cisplatin + Fluorouracil + Sapitinib | Cisplatin Fluorouracil Sapitinib | 0 | 0 |
MK2206 + Sapitinib | MK2206 Sapitinib | 0 | 0 |
Paclitaxel + Sapitinib | Paclitaxel Sapitinib | 0 | 0 |
Sapitinib | Sapitinib | 1 | 0 |