Sapitinib
Drug Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Drug Name | Sapitinib |
| Trade Name | |
| Synonyms | AZD8931|AZD-8931 |
| Drug Descriptions |
Sapitinib (AZD-8931) binds to and inhibits the ERBB family members EGFR, ERBB2 (HER2), and ERBB3, which may lead to decreased tumor cell proliferation and increased apoptosis (PMID: 20145185, PMID: 31765988). |
| DrugClasses | EGFR Inhibitor (Pan) 63 HER2 Inhibitor 44 HER3 Inhibitor 1 |
| CAS Registry Number | 848942-61-0 |
| NCIT ID | C77887 |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Atezolizumab + Sapitinib | Atezolizumab Sapitinib | 0 | 0 |
| Capecitabine + Oxaliplatin + Sapitinib | Capecitabine Oxaliplatin Sapitinib | 0 | 0 |
| Cisplatin + Fluorouracil + Sapitinib | Cisplatin Fluorouracil Sapitinib | 0 | 0 |
| MK2206 + Sapitinib | MK2206 Sapitinib | 0 | 0 |
| Paclitaxel + Sapitinib | Paclitaxel Sapitinib | 0 | 0 |
| Sapitinib | Sapitinib | 1 | 0 |
CKB BOOST