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Drug Name | Depatuxizumab mafodotin |
Trade Name | |
Synonyms | ABT-414|depatux-m |
Drug Descriptions |
Depatuxizumab mafodotin (ABT-414) is an antibody-drug conjugate comprising an EGFR-targeted antibody linked to an anti-microtubule drug, which delivers the cytotoxic agent to EGFR-expressing cells, potentially resulting in increased tumor cell death and decreased growth of EGFR-overexpressing tumors (PMID: 26846818, PMID: 29075855, PMID: 31747009, PMID: 32371586). |
DrugClasses | EGFR Antibody 60 |
CAS Registry Number | 1585973-65-4 |
NCIT ID | C105612 |