Valrubicin
Drug Detail
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| Drug Name | Valrubicin |
| Trade Name | Valstar |
| Synonyms | Antibiotic Ad 32|AD-32 |
| Drug Descriptions |
Valstar (valrubicin) is an anthracycline that is metabolized into compounds that inhibit topoisomerase II, resulting in inhibition of DNA synthesis and potentially leading to decreased tumor growth (PMID: 19145271, PMID: 20554745). Valstar (valrubicin) is FDA-approved for treatment of BCG-refractory urinary bladder carcinoma in situ (FDA.gov). |
| DrugClasses | Chemotherapy - Anthracycline 13 TOPO2 inhibitor 5 |
| CAS Registry Number | 56124-62-0 |
| NCIT ID | C1340 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Gemcitabine + Interferon gamma + Mitomycin C + Valrubicin | Gemcitabine Interferon gamma Mitomycin C Valrubicin | 0 | 0 |
| Valrubicin | Valrubicin | 0 | 1 |
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