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Drug Name Interferon gamma
Trade Name Actimmune
Synonyms gamma interferon|IFN-G|recombinant interferon gamma
Drug Descriptions

Interferon gamma is a cytokine that binds IFN-gamma receptors, leading to pleiotropic effects, including stimulating antibody-dependent cytotoxicity and enhanced natural killer cell activity against tumor cells and the activation of caspases, leading to apoptosis of malignant cells (PMID: 14525967).

DrugClasses
CAS Registry Number 98059-61-1
NCIT ID C583

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Therapy Name Drugs Efficacy Evidence Clinical Trials
DNX-2401 + Interferon gamma DNX-2401 Interferon gamma 0 1
Gemcitabine + Interferon gamma + Mitomycin C + Valrubicin Gemcitabine Interferon gamma Mitomycin C Valrubicin 0 0
Interferon gamma Interferon gamma 0 3
Interferon gamma + Paclitaxel + Pertuzumab + Trastuzumab Interferon gamma Paclitaxel Pertuzumab Trastuzumab 0 1
Interferon gamma + Peginterferon alfa-2b Interferon gamma Peginterferon alfa-2b 0 1
Interferon gamma + Pembrolizumab Interferon gamma Pembrolizumab 0 1


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