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Drug Name | LY3023414 |
Trade Name | |
Synonyms | Samotolisib|LY-3023414|LY 3023414 |
Drug Descriptions |
Samotolisib (LY3023414) is an ATP competitive inhibitor of PI3K/mTOR, inhibits signaling of the PI3K/mTOR pathway, and has demonstrated antiproliferative activity against tumor cells (PMID: 24387334, PMID: 31880826). |
DrugClasses | mTOR Inhibitor 51 PI3K Inhibitor (Pan) 42 |
CAS Registry Number | 1386874-06-1 |
NCIT ID | C121817 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Abemaciclib + Fulvestrant + LY3023414 | Abemaciclib Fulvestrant LY3023414 | 0 | 1 |
Abemaciclib + Letrozole + LY3023414 | Abemaciclib LY3023414 Letrozole | 0 | 1 |
Abemaciclib + LY3023414 | Abemaciclib LY3023414 | 0 | 2 |
Enzalutamide + LY3023414 | Enzalutamide LY3023414 | 0 | 0 |
Letrozole + LY3023414 | LY3023414 Letrozole | 0 | 1 |
LY3023414 | LY3023414 | 9 | 10 |
LY3023414 + LY3039478 | LY3023414 LY3039478 | 0 | 1 |
LY3023414 + LY3214996 | LY3023414 LY3214996 | 0 | 0 |
LY3023414 + Midazolam | LY3023414 Midazolam | 0 | 1 |
LY3023414 + Prexasertib | LY3023414 Prexasertib | 1 | 1 |