Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name LY3023414
Trade Name
Synonyms Samotolisib|LY-3023414|LY 3023414
Drug Descriptions

Samotolisib (LY3023414) is an ATP competitive inhibitor of PI3K/mTOR, inhibits signaling of the PI3K/mTOR pathway, and has demonstrated antiproliferative activity against tumor cells (PMID: 24387334, PMID: 31880826).

DrugClasses mTOR Inhibitor 51 PI3K Inhibitor (Pan) 42
CAS Registry Number 1386874-06-1
NCIT ID C121817

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Abemaciclib + Fulvestrant + LY3023414 Abemaciclib Fulvestrant LY3023414 0 1
Abemaciclib + Letrozole + LY3023414 Abemaciclib LY3023414 Letrozole 0 1
Abemaciclib + LY3023414 Abemaciclib LY3023414 0 2
Enzalutamide + LY3023414 Enzalutamide LY3023414 0 0
Letrozole + LY3023414 LY3023414 Letrozole 0 1
LY3023414 LY3023414 9 10
LY3023414 + LY3039478 LY3023414 LY3039478 0 1
LY3023414 + LY3214996 LY3023414 LY3214996 0 0
LY3023414 + Midazolam LY3023414 Midazolam 0 1
LY3023414 + Prexasertib LY3023414 Prexasertib 1 1


Additional content available in CKB BOOST