Seliciclib
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| Drug Name | Seliciclib |
| Trade Name | |
| Synonyms | Roscovitine|CYC202 |
| Drug Descriptions |
Roscovotine (seliciclib) inhibits Cdc2, Cdk2 and Cdk5, which results in disruption of cell-cycle progression and decreased cell proliferation (PMID: 9030781, PMID: 9366565, PMID: 20822897) |
| DrugClasses | CDK2 Inhibitor 31 CDK5 Inhibitor 8 |
| CAS Registry Number | 186692-46-6 |
| NCIT ID | C62783 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Aldoxorubicin + Seliciclib | Aldoxorubicin Seliciclib | 0 | 0 |
| Alvocidib + Seliciclib | Alvocidib Seliciclib | 0 | 0 |
| Doxorubicin + Seliciclib | Doxorubicin Seliciclib | 2 | 0 |
| Sapacitabine + Seliciclib | Sapacitabine Seliciclib | 0 | 1 |
| Seliciclib | Seliciclib | 9 | 0 |
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