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Drug Detail
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| Drug Name | Dalantercept |
| Trade Name | |
| Synonyms | ACE-041|ALK1-Fc |
| Drug Descriptions |
Dalantercept (ACE-041) is an ALK1 ligand trap composed of the ALK1 extracellular domain linked to the IgG Fc region, which binds to ALK1 ligands and prevents binding to the receptor, potentially leading to decreased tumor angiogenesis and growth and increased sensitivity to chemotherapeutic agents (PMID: 25708802, PMID: 26373572, PMID: 20124460, PMID: 30951193). |
| DrugClasses | ALK Inhibitor 33 |
| CAS Registry Number | 1186210-24-1 |
| NCIT ID | C88296 |
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