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Drug Name Axitinib
Trade Name Inlyta
Synonyms AG-013736|AG013736
Drug Descriptions

Inlyta (axitinib) inhibits the VEGFRs, PDGFR, and KIT, potentially resulting in decreased angiogenesis and reduced tumor growth (PMID: 16027439, PMID: 25709499). Inlyta (axitinib) is approved for renal cell carcinoma (FDA.gov).

DrugClasses KIT Inhibitor 57 PDGFR Inhibitor (Pan) 30 VEGFR Inhibitor (Pan) 36
CAS Registry Number 319460-85-0
NCIT ID C38718

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Avelumab + Axitinib Avelumab Axitinib 0 8
Avelumab + Axitinib + Bavituximab Avelumab Axitinib Bavituximab 0 1
Avelumab + Axitinib + Palbociclib Avelumab Axitinib Palbociclib 0 2
Axitinib Axitinib 12 27
Axitinib + AZD0156 AZD0156 Axitinib 0 0
Axitinib + Bevacizumab Axitinib Bevacizumab 0 0
Axitinib + Bosutinib Axitinib Bosutinib 0 1
Axitinib + Carboplatin + Paclitaxel Axitinib Carboplatin Paclitaxel 0 0
Axitinib + Carotuximab Axitinib Carotuximab 0 1
Axitinib + Crizotinib Axitinib Crizotinib 0 1
Axitinib + Dalantercept Axitinib Dalantercept 0 1
Axitinib + Erlotinib Axitinib Erlotinib 0 1
Axitinib + Fluorouracil + Irinotecan + Leucovorin Axitinib Fluorouracil Irinotecan Leucovorin 0 0
Axitinib + Fluorouracil + Leucovorin + Oxaliplatin Axitinib Fluorouracil Leucovorin Oxaliplatin 0 0
Axitinib + Gemcitabine Axitinib Gemcitabine 0 0
Axitinib + HC-5404-FU Axitinib HC-5404-FU 0 0
Axitinib + Hydroxychloroquine Axitinib Hydroxychloroquine 0 1
Axitinib + INCB099280 Axitinib INCB099280 0 1
Axitinib + Ipilimumab Axitinib Ipilimumab 0 1
Axitinib + Ipilimumab + Nivolumab Axitinib Ipilimumab Nivolumab 0 1
Axitinib + M8891 Axitinib M8891 1 0
Axitinib + MEDI5752 Axitinib MEDI5752 0 1
Axitinib + MK-3475A + Pembrolizumab Axitinib MK-3475A Pembrolizumab 0 1
Axitinib + Nivolumab Axitinib Nivolumab 0 6
Axitinib + Nivolumab + NKTR-214 Axitinib NKTR-214 Nivolumab 0 1
Axitinib + Osimertinib Axitinib Osimertinib 0 0
Axitinib + Pembrolizumab Axitinib Pembrolizumab 0 10
Axitinib + Pembrolizumab + Selenomethionine Axitinib Pembrolizumab Selenomethionine 0 1
Axitinib + PF-04518600 Axitinib PF-04518600 0 1
Axitinib + PF-06801591 + SGN-TGT Axitinib PF-06801591 SGN-TGT 0 1
Axitinib + Radiotherapy Axitinib Radiotherapy 0 0
Axitinib + RO7247669 Axitinib RO7247669 0 1
Axitinib + RO7247669 + Tiragolumab Axitinib RO7247669 Tiragolumab 0 1
Axitinib + Selenomethionine Axitinib Selenomethionine 0 1
Axitinib + Talazoparib Axitinib Talazoparib 0 2
Axitinib + Toripalimab-tpzi Axitinib Toripalimab-tpzi 0 0
Axitinib + Vemurafenib Axitinib Vemurafenib 1 0
Axitinib + X4P-001 Axitinib X4P-001 0 0


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