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Drug Name | Ascrinvacumab |
Trade Name | |
Synonyms | PF-03446962|GT90001|GT-90001|GT 90001 |
Drug Descriptions |
Ascrinvacumab (PF-03446962) is a monoclonal antibody that binds and inhibits activin-like receptor kinase 1 (ALK-1), potentially resulting in decreased tumor angiogenesis and proliferation (PMID: 31444620). |
DrugClasses | |
CAS Registry Number | 1463459-96-2 |
NCIT ID | C91073 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Ascrinvacumab | Ascrinvacumab | 0 | 0 |
Ascrinvacumab + Nivolumab | Ascrinvacumab Nivolumab | 0 | 1 |
Ascrinvacumab + Regorafenib | Ascrinvacumab Regorafenib | 0 | 1 |