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Drug Name | Marizomib |
Trade Name | |
Synonyms | NPI-0052|ML 858|Salinosporamide A|Salinosporin A |
Drug Descriptions |
Marizomib (NPI-0052) is an irreversible inhibitor of the 20S proteasome, which leads to cell cycle arrest and apoptosis in tumor cells (PMID: 16891470, PMID: 29076150). |
DrugClasses | |
CAS Registry Number | 437742-34-2 |
NCIT ID | C64634 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Bevacizumab + Marizomib | Bevacizumab Marizomib | 0 | 1 |
Dexamethasone + Marizomib + Pomalidomide | Dexamethasone Marizomib Pomalidomide | 0 | 0 |
Marizomib | Marizomib | 0 | 2 |
Marizomib + Panobinostat | Marizomib Panobinostat | 0 | 1 |
Marizomib + Tinostamustine | Marizomib Tinostamustine | 0 | 0 |
Marizomib + Vorinostat | Marizomib Vorinostat | 0 | 0 |