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Drug Name | Vorinostat |
Trade Name | Zolinza |
Synonyms | SAHA|L-001079038|MSK390 |
Drug Descriptions |
Zolinza (vorinostat) inhibits HDAC activity, resulting in cell-cycle arrest, decreased proliferation, and increased differentiation of tumor cells (PMID: 9501205, PMID: 11731433, PMID: 11016644). Zolinza (vorinostat) is FDA approved for use in cutaneous T-cell lymphoma (FDA.gov). |
DrugClasses | HDAC Inhibitor 45 |
CAS Registry Number | 149647-78-9 |
NCIT ID | C1796 |