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Drug Name | Savolitinib |
Trade Name | |
Synonyms | HMPL-504|AZD6094|AZD-6094|Volitinib |
Drug Descriptions |
Savolitinib (AZD6094) is a selective MET inhibitor, which inhibits MET kinase activity, resulting in decreased downstream signaling, and may inhibit growth of MET-expressing tumors (PMID: 25248999, PMID: 32027846, PMID: 30952639). |
DrugClasses | MET Inhibitor 59 |
CAS Registry Number | 1313725-88-0 |
NCIT ID | C104732 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Afatinib + Savolitinib | Afatinib Savolitinib | 0 | 0 |
Cetuximab + Savolitinib | Cetuximab Savolitinib | 0 | 1 |
Durvalumab + Savolitinib | Durvalumab Savolitinib | 0 | 1 |
Furmonertinib + Savolitinib | Furmonertinib Savolitinib | 0 | 0 |
Gefitinib + Savolitinib | Gefitinib Savolitinib | 0 | 0 |
Itraconazole + Savolitinib | Itraconazole Savolitinib | 0 | 0 |
Lorlatinib + Savolitinib | Lorlatinib Savolitinib | 0 | 0 |
Moxifloxacin + Savolitinib | Moxifloxacin Savolitinib | 0 | 0 |
Osimertinib + Savolitinib | Osimertinib Savolitinib | 0 | 5 |
Savolitinib | Savolitinib | 0 | 7 |