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Drug Name | PHA-665752 |
Trade Name | |
Synonyms | PHA665752|PHA 665752 |
Drug Descriptions |
PHA-665752 is a small molecule inhibitor of MET, which inhibits MET kinase activity and downstream signaling, potentially resulting in increased apoptosis and decreased proliferation and migration of tumor cells (PMID: 14612533, PMID: 29456739). |
DrugClasses | MET Inhibitor 59 |
CAS Registry Number | 477575-56-7 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Conteltinib + PHA-665752 | Conteltinib PHA-665752 | 0 | 0 |
Gefitinib + Linsitinib + PHA-665752 | Gefitinib Linsitinib PHA-665752 | 0 | 0 |
Gefitinib + PHA-665752 | Gefitinib PHA-665752 | 0 | 0 |
PHA-665752 | PHA-665752 | 1 | 0 |
PHA-665752 + Sonidegib | PHA-665752 Sonidegib | 0 | 0 |
PHA-665752 + Xentuzumab | PHA-665752 Xentuzumab | 0 | 0 |