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Drug Name | PKF118-310 |
Trade Name | |
Synonyms | |
Drug Descriptions |
PKF118-310 inhibits KDM4A activity (PMID: 27767379) and the CTNNB1/TCF interaction, which results in apoptosis and anti-tumor activity (PMID: 19662654). |
DrugClasses | CTNNB1 Inhibitor 27 KDM4 Inhibitor 4 |
CAS Registry Number | NA |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
GSK-J4 + PKF118-310 | GSK-J4 PKF118-310 | 0 | 0 |
Imatinib + PKF118-310 | Imatinib PKF118-310 | 1 | 0 |
PKF118-310 | PKF118-310 | 1 | 0 |