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Drug Name CRS-207
Trade Name
Synonyms CRS207|CRS 207
Drug Descriptions

CRS-207 is a vaccine comprised of a live-attenuated strain of Listeria monocytogenes engineered to express human mesothelin, which induces anti-tumor immune response towards mesothelin-positive tumor cells (PMID: 22147941, PMID: 32273276, PMID: 32132105).

DrugClasses
CAS Registry Number NA
NCIT ID C74055

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Therapy Name Drugs Efficacy Evidence Clinical Trials
CRS-207 CRS-207 0 2
CRS-207 + Cyclophosphamide + Epacadostat + GVAX pancreatic cancer vaccine + Pembrolizumab CRS-207 Cyclophosphamide Epacadostat GVAX pancreatic cancer vaccine Pembrolizumab 0 1
CRS-207 + Cyclophosphamide + GVAX pancreatic cancer vaccine + Ipilimumab + Nivolumab CRS-207 Cyclophosphamide GVAX pancreatic cancer vaccine Ipilimumab Nivolumab 0 1
CRS-207 + Epacadostat + Pembrolizumab CRS-207 Epacadostat Pembrolizumab 0 1
CRS-207 + GVAX pancreatic cancer vaccine CRS-207 GVAX pancreatic cancer vaccine 0 0
CRS-207 + Ipilimumab + Nivolumab CRS-207 Ipilimumab Nivolumab 0 1
CRS-207 + Ipilimumab + Pembrolizumab + Tadalafil CRS-207 Ipilimumab Pembrolizumab Tadalafil 0 1
CRS-207 + Pembrolizumab CRS-207 Pembrolizumab 0 2


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