Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | Epacadostat |
Trade Name | |
Synonyms | INCB024360|INCB 024360|INCB-024360 |
Drug Descriptions |
Epacadostat (INCB024360) inhibits indoleamine 2,3-dioxygenase 1 (IDO1) to prevent conversion of tryptophan to kynurenine, potentially resulting in increased proliferation of T-cells and natural killer cells and enhanced anti-tumor immune response (PMID: 20197554). |
DrugClasses | IDO1 Inhibitor 12 |
CAS Registry Number | 1204669-58-8 |
NCIT ID | C92582 |