Birinapant
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| Drug Name | Birinapant |
| Trade Name | |
| Synonyms | TL32711 |
| Drug Descriptions |
TL32711 (birinapant) is a a bivalent SMAC-mimetic compound, which binds to and inhibits Inhibitor of Apoptosis proteins (IAPs), leading to tumor cell death (PMID: 24563541, PMID: 26566079). |
| DrugClasses | SMAC Mimetic 8 |
| CAS Registry Number | 1260251-31-7 |
| NCIT ID | C88295 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Birinapant | Birinapant | 1 | 2 |
| Birinapant + Fulvestrant | Birinapant Fulvestrant | 0 | 0 |
| Birinapant + Pembrolizumab | Birinapant Pembrolizumab | 0 | 1 |
| Birinapant + Radiotherapy | Birinapant Radiotherapy | 0 | 0 |
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