Sipuleucel-T
Drug Detail
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| Drug Name | Sipuleucel-T |
| Trade Name | Provenge |
| Synonyms | APC 8015 |
| Drug Descriptions |
Provenge (sipuleucel-T) is composed of autologous dendritic cells exposed to a PAP-GCSF fusion protein (PA2024), which stimulates a cytotoxic immune response towards PAP-expressing tumor cells (PMID: 25565923, PMID: 25708576). Provenge (sipuleucel-T) is FDA-approved for use in patients with metastatic castration-resistant prostate cancer (FDA.gov). |
| DrugClasses | |
| CAS Registry Number | 917381-47-6 |
| NCIT ID | C1985 |
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