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Drug Name | Trabedersen |
Trade Name | |
Synonyms | AP 12009|OT-101|OT101 |
Drug Descriptions |
Trabedersen (AP 12009) is an antisense oligonucleotide that inhibits TGFB2 translation, which may result in decreased proliferation and migration of cancer cells (PMID: 21366804, PMID: 31692434). |
DrugClasses | TGFB inhibitor 5 |
CAS Registry Number | 925681-61-4 |
NCIT ID | C80066 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Atezolizumab + Trabedersen | Atezolizumab Trabedersen | 0 | 1 |
Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin + Trabedersen | Fluorouracil Irinotecan Leucovorin Oxaliplatin Trabedersen | 0 | 1 |
Pembrolizumab + Trabedersen | Pembrolizumab Trabedersen | 0 | 2 |
Trabedersen | Trabedersen | 0 | 0 |