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Drug Name | Ulocuplumab |
Trade Name | |
Synonyms | BMS-936564|MDX1338 |
Drug Descriptions |
Ulocuplumab (BMS-936564) is a monoclonal antibody that binds to CXCR4 and prevents binding of SDF-1 (CXCL12), potentially resulting in increased apoptosis and decreased migration of tumor cells (PMID: 23213054, PMID: 31672767). |
DrugClasses | CXCR4 Inhibitor 15 |
CAS Registry Number | 1375830-34-4 |
NCIT ID | C95755 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Bortezomib + Dexamethasone + Ulocuplumab | Bortezomib Dexamethasone Ulocuplumab | 0 | 1 |
Cytarabine + Ulocuplumab | Cytarabine Ulocuplumab | 0 | 1 |
Dexamethasone + Lenalidomide + Ulocuplumab | Dexamethasone Lenalidomide Ulocuplumab | 0 | 1 |
Ibrutinib + Ulocuplumab | Ibrutinib Ulocuplumab | 0 | 1 |
Ulocuplumab | Ulocuplumab | 0 | 1 |