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Drug Name | ASP-1929 |
Trade Name | |
Synonyms | Cetuximab sarotalocan|Cetuximab-IRDye-700DX|RM-1929|Cet-IR700|ASP1929 |
Drug Descriptions |
ASP1929 (RM-1929) is comprised of the EGFR antibody cetuximab conjugated to the dye IR700, which binds to EGFR-expressing cells and disrupts the cell membrane upon exposure to near-infared light, and may induce antitumor activity (NCI Drug Dictionary, J Clin Oncol 42, 2024 (suppl 16; abstr 6083)). |
DrugClasses | EGFR Antibody 60 |
CAS Registry Number | 2166339-33-7 |
NCIT ID | C121850 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
ASP-1929 | ASP-1929 | 0 | 2 |
ASP-1929 + Cemiplimab | ASP-1929 Cemiplimab | 0 | 1 |
ASP-1929 + Pembrolizumab | ASP-1929 Pembrolizumab | 0 | 1 |