Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | Indoximod |
Trade Name | |
Synonyms | D-1MT|1-MT|NLG-8189 |
Drug Descriptions |
Indoximod (D-1MT) inhibits indoleamine 2,3-dioxygenase 1 (IDO1), which decreases metabolism of tryptophan to kynurenine, potentially resulting in increased T-cell proliferation and activation and enhanced anti-tumor immune response (PMID: 17234791, PMID: 32637034, PMID: 34117113). |
DrugClasses | IDO1 Inhibitor 12 |
CAS Registry Number | 110117-83-4 |
NCIT ID | C71535 |