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Drug Name | Tirapazamine |
Trade Name | Tirazone |
Synonyms | SR4233|WIN 59075 |
Drug Descriptions |
Tirazone (tirapazamine) is a hypoxia-activated prodrug that induces DNA damage within hypoxic regions of tumors, potentially providing antineoplastic activity (PMID: 18666379, PMID: 32543771). |
DrugClasses | |
CAS Registry Number | 27314-97-2 |
NCIT ID | C1464 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Pembrolizumab + Tirapazamine | Pembrolizumab Tirapazamine | 0 | 1 |
Tirapazamine | Tirapazamine | 0 | 2 |