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Drug Name | Mirvetuximab Soravtansine |
Trade Name | Elahere |
Synonyms | IMGN853|M9346A-sulfo-SPDB-DM4|mirvetuximab soravtansine-gynx |
Drug Descriptions |
Elahere (mirvetuximab soravtansine) is an antibody-drug conjugate comprised of an antibody directed against FOLR1 linked to the tubulin polymerization-inhibiting drug DM4, leading to cell death in Folr1-expressing tumors (PMID: 26136852, PMID: 25904506). Elahere (mirvetuximab soravtansine) is FDA approved for use in patients with FOLR1-positive, platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer, who have received one to three prior systemic treatments (FDA.gov). |
DrugClasses | FOLR1-targeted Therapy 24 |
CAS Registry Number | 1453084-37-1 |
NCIT ID | C102566 |