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Drug Name | MK-8353 |
Trade Name | |
Synonyms | SCH900353 |
Drug Descriptions |
MK-8353 is an analog of SCH772984, which targets both Erk1 and Erk2 and may inhibit cell growth (PMID: 25142146, PMID: 29467321). |
DrugClasses | ERK Inhibitor (pan) 21 |
CAS Registry Number | 1184173-73-6 |
NCIT ID | C104045 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Lifirafenib + MK-8353 | Lifirafenib MK-8353 | 2 | 0 |
MK-8353 | MK-8353 | 2 | 1 |
MK-8353 + Pembrolizumab | MK-8353 Pembrolizumab | 0 | 1 |
MK-8353 + Selumetinib | MK-8353 Selumetinib | 0 | 1 |