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Drug Name | RO6958688 |
Trade Name | |
Synonyms | RG7802|Cibisatamab|CEA-TCB|RO-6958688 |
Drug Descriptions |
RO6958688 (cibisatamab) is a bispecific antibody that binds to CD3 and human anti-carcinoembryonic antigen (CEA) simultaneously, which may lead to cytotoxic immune response against CEA-positive tumor cells (PMID: 30982469). |
DrugClasses | CD3 Antibody 99 |
CAS Registry Number | 1855925-27-7 |
NCIT ID | C120097 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Atezolizumab + Obinutuzumab + RO6958688 | Atezolizumab Obinutuzumab RO6958688 | 0 | 1 |
Atezolizumab + RO6958688 | Atezolizumab RO6958688 | 0 | 2 |
Obinutuzumab + RO6958688 + RO7122290 | Obinutuzumab RO6958688 RO7122290 | 0 | 1 |
RO6958688 | RO6958688 | 0 | 0 |